The American College of Lifestyle Medicine annual conference, taking place from October 29 to November 1 in Denver, will focus on how to implement the principles of lifestyle medicine into clinical practice. The conference will explore the benefits of exercise, a healthy diet, and good sleep, and how prescribing these lifestyle behavior interventions could revolutionize healthcare. The conference will cover the six pillars of lifestyle medicine: whole-food, plant-predominant eating pattern, regular physical activity, stress management, restorative sleep, social connection, and avoidance of risky substances. Attendees will have the opportunity to experience these pillars firsthand through a whole-food, plant-predominant diet and a 5K fun run. The conference is expected to attract around 2,000 healthcare professionals and will offer virtual attendance options. CME credits will also be available. The conference is recommended for healthcare providers who are interested in transforming their practice and improving patient outcomes through lifestyle medicine interventions.